"In conclusion, these data support the addition of POTS to a growing number of cardiovascular entities with an autoimmune pathophysiology." Authors
The Rituximab findings, the female predominance, the increasing evidence of heritability, the inflammatory component, and the common infectious trigger Read more [...]
Specifically, we suggest that CFS is caused by sustained arousal. Wyller
Brun Wyller has raised controversy in Norway for his drug/behavioral approach to chronic fatigue in service of a hypothesis asserting that 'sustained arousal' (increased sympathetic nervous system (fight or flight)) activity Read more [...]
The Polyvagal Theory
The autonomic nervous system is traditionally described as consisting of two antagonistic and balanced branches, the sympathetic and the parasympathetic system. The sympathetic system or the "fight or flight" arousal system kicks into gear when we perceive threats. When that Read more [...]
(Dr. Newton’s studies suggest the muscles of people with ME/CFS are not efficiently removing the acids that build up during exercise. It’s possible this acid buildup is contributing to the hyperventilation, and, of course, the exercise problems in ME/CFS. Earlier she mentioned she was determining Read more [...]
Is ME/CFS/FM bigger than we think? Does it consist of a complex of disorders such as ME/CFS/FM/POTS/Autonomic Neuropathy/IBS/ (fill in the blank) that share similar types of onset, symptoms and some lab results. Let's see how that question is shaking out.
Check out Pt I of the Read more [...]
The 24th International Symposium on the Autonomic Nervous System was chock full of potential insights for people with chronic fatigue syndrome. We used Dysautonomia International's excellent overview of the relevant studies as a starting point. (Thanks to Issie for alerting me to the overview.)
Is Read more [...]
Complex Regional Pain Syndrome and Spreading neuroinflammation and autoimmunity – a model for ME/CFS and fibromyalgia?
Neuroinflammation in ME/CFS and Fibromyalgia
In previous articles I've been trying to set out, at some length and based on converging evidence, a proposed model of ME/CFS and a Read more [...]
...There is considerable evidence to highlight an abnormality of the autonomic nervous system as a unifying pathological factor. Newton et. Al.
Newton's shown that people with chronic fatigue syndrome tend to display an interrelated trio of problems; increased acid in their muscles during Read more [...]