Archive for Brain – Page 2

Your Brain Without Energy: Broken Brain Energy Loop Wipes Out Cognitive Functioning in GWS Patients with Chronic Fatigue Syndrome

(Exercise stress tests suggest a process that provides energy to the brain during exercise and intense mental activity may be broken and causing severe cognitive dysfunction in one group of GWS/ME/CFS patients (decreasers).  A second GWS/ME/CFS group (increasers) with an intact brain lactate processing Read more [...]

The Immune in Neuroimmune: Cytokines, Bugs and NK Cells – Part IV of the Neuroinflammatory Series Continues

(We're in the windup phase of Marco's Neuroinflammatory Series as he explores the role the immune system and pathogens  play in producing the neuroinflammatory state that may underlie chronic fatigue syndrome (ME/CFS) For more on Marco's Neuroinflammatory Series on ME/CFS C - IMMUNE FINDINGS, Read more [...]

Unusual Type of Nerve Damage Causes Fatigue and Pain in People with Gulf War Illness and Chronic Fatigue Syndrome

(Dr. Baraniuk finds damage to a critical nerve pathway that connects regions of the brain involved in fatigue and pain production and autonomic nervous system regulation. The damage, which affects the integrity of the nerve axons, is unusual and suggests GWS and perhaps ME/CFS  are not related to Read more [...]

When Definitions Obscure: A Neuroinflammatory View of Chronic Fatigue Syndrome Pt. IV

A – A PERSONAL PERSPECTIVE ON 'ME/CFS'  I want to make a controversial and potentially unpopular proposal: that ME/CFS is not a discrete disease in any objective sense and that attempting to more rigorously define a 'pure' ME/CFS cohort is futile.   In Parts I to III, I set out what I suggest Read more [...]

Scared Stiff? Exploring Anxiety, Autoimmunity and Infection in Stiff Person Syndrome – A Possible Model For Chronic Fatigue Syndrome

  (Marco digs into a controversial subject in this second of two blogs on Stiff Person Syndrome and ME/CFS - "Is the depression/anxiety present in Stiff Person Syndrome and, possibly by reflection, chronic fatigue syndrome (ME/CFS), a consequence of having a difficult disease or is it an inherent Read more [...]

Does A Rare Neurological Disorder Provide Clues to ME/CFS and FM? The Neuroinflammation Series Pt 3a

(Marco's first two Neuroinflammatory blogs lead us into sensory gating and glutatmate excitoxoicity and now he dives into a rare neurological disorder called Stiff Person Syndrome (SPS) (sometimes misdiagnosed as Fibromyalgia) with factors (high glutamate levels,  increased sensitivity to stimulation, Read more [...]

Your Brain on Fire: Big NIH Chronic Fatigue Syndrome Study To Look For Biomarker Based on Brain Glutathione Levels

Two million dollars for chronic fatigue syndrome (ME/CFS) research...You don't hear those words very often. The NIH just gave Dr. Shungu and associates a big two million dollar grant to peer into chronic fatigue syndrome patients brains. This is the kind of study that makes you love the NIH; it's Read more [...]

Glutamate – One More Piece in the Chronic Fatigue Syndrome (ME/CFS) Puzzle? The Neuroinflammatory Series Pt. II

(In a second of four-part series of papers elucidating a neuro-inflammatory model of chronic fatigue syndrome, Marco examines a possibility that could explain many symptoms and issue not just in ME/CFS but in other neurological disorders. Learn more about Marco here - Cort).  Pt 1 of the Neuroinflammatory Read more [...]