Archive for Research – Page 2

The ‘Mono’ Studies: Looking for Answers to Chronic Fatigue Syndrome

Studies indicate that when you ask an adolescent what triggered their Chronic Fatigue Syndrome, up to three-quarters are going to say mononucleosis (or glandular fever) or some other sudden, often vicious mono-like illness. With fully fifty percent of them testing positive for mono, it's no wonder Read more [...]

The Devil Is In The Details – A Herpes Simplex Virus Inquiry For Fibromyalgia and Chronic Fatigue Syndrome

(As we await the outcome of the Pridgen antiviral herpes simplex trial in Fibromyalgia, Albert Chang takes a deeper look at herpes simplex  viruses.) Two herpesviruses, Epstein-Barr virus (EBV) and HHV-6, have been of interest in chronic fatigue syndrome for decades.  However, it was not Read more [...]

‘Sustained Arousal’ Hypothesis Not Sustained: Wyller’s Clonidine Trial for Chronic Fatigue Syndrome Fails

Specifically, we suggest that CFS is caused by sustained arousal. Wyller Brun Wyller has raised controversy in Norway for his drug/behavioral approach to chronic fatigue in service of a hypothesis asserting that 'sustained arousal' (increased sympathetic nervous system (fight or flight)) activity Read more [...]

“A Regulatory Barrier to Change” : Why Women Get More Stuck with Chronic Fatigue Syndrome Than Men – A Model of ME/CFS Emerges

"The HPA axis [is] a major part of the neuroendocrine system that controls reactions to stress and regulates many body processes, including digestion, the immune system, mood and emotions, sexuality and energy storage and expenditure." Wikipedia The HPA axis and low cortisol readings were Read more [...]

Poor Oxygen Uptake May Be at the Core of the Exercise Problems in Chronic Fatigue Syndrome

Taking the Next, er, Step First you document the problem, then you try to figure out what's causing it.  At least three research groups have decided it's time to move past documenting a messed up  energy production system in ME/CFS and to begin figuring what's causing it. Over the next couple Read more [...]

What’s Up in 2014? A Look Ahead for Chronic Fatigue Syndrome

What's up in 2014? Federal funding still sucks, but it's clear that the Research Foundations and non-profits are finding a way.  As the list of studies or trials ending in 2014 indicates, we're going to learn a lot about chronic fatigue syndrome this year. Treatment UK Rituximab Trial Underway - Invest Read more [...]

Small Nerve Fiber Neuropathy Commonly Found in Fibromyalgia (and Linked to Central Sensitization)

Sometimes you don't know if you should laugh or cry. This study starts off with a list of abnormal findings in fibromyalgia: there's the central nervous system sensitization which involves increased activity in the brain’s pain processing regions, increased responsiveness in regions that that process Read more [...]

Moving Targets: Fibromyalgia and Chronic Fatigue Syndrome Over Time

Fibromyalgia "The human brain displays a high degree of plasticity, and gray matter and white matter change throughout the life span." Authors Recently we saw that more intense connections from the one part of the brain  (prefrontal cortex) to another part of the brain (limbic system) appear to Read more [...]