Archive for Research – Page 2

Stress By Any Other Name: Inflammation, ‘Stress’ and Chronic Fatigue and Fibromalygia: An Inquiry

“Sometimes I think I'm so overwhelmed that the little, simple things that other people do or say really set me off emotionally, which we know only makes the pain worse.“ Person with Fibromyalgia One of the most puzzling aspects of my Chronic Fatigue Syndrome/Fibromyaglia has been my body's Read more [...]

The Energy Disorders: Diabetes, ME/CFS and FM – Can Diabetes Tell Us Anything About Chronic Fatigue Syndrome and Fibromyalgia?

  Small Fiber Neuropathy In the last year or so we've seen four studies published (1,2,3,4) that have found objective evidence of small fiber polyneuropathy in FM patients suggesting that the 'central sensitization' theory of FM may be at best incomplete. In fact peripheral nerve damage may be driving Read more [...]

The ‘Mono’ Studies: Looking for Answers to Chronic Fatigue Syndrome

Studies indicate that when you ask an adolescent what triggered their Chronic Fatigue Syndrome, up to three-quarters are going to say mononucleosis (or glandular fever) or some other sudden, often vicious mono-like illness. With fully fifty percent of them testing positive for mono, it's no wonder Read more [...]

The Devil Is In The Details – A Herpes Simplex Virus Inquiry For Fibromyalgia and Chronic Fatigue Syndrome

(As we await the outcome of the Pridgen antiviral herpes simplex trial in Fibromyalgia, Albert Chang takes a deeper look at herpes simplex  viruses.) Two herpesviruses, Epstein-Barr virus (EBV) and HHV-6, have been of interest in chronic fatigue syndrome for decades.  However, it was not Read more [...]

‘Sustained Arousal’ Hypothesis Not Sustained: Wyller’s Clonidine Trial for Chronic Fatigue Syndrome Fails

Specifically, we suggest that CFS is caused by sustained arousal. Wyller Brun Wyller has raised controversy in Norway for his drug/behavioral approach to chronic fatigue in service of a hypothesis asserting that 'sustained arousal' (increased sympathetic nervous system (fight or flight)) activity Read more [...]

“A Regulatory Barrier to Change” : Why Women Get More Stuck with Chronic Fatigue Syndrome Than Men – A Model of ME/CFS Emerges

"The HPA axis [is] a major part of the neuroendocrine system that controls reactions to stress and regulates many body processes, including digestion, the immune system, mood and emotions, sexuality and energy storage and expenditure." Wikipedia The HPA axis and low cortisol readings were Read more [...]

Poor Oxygen Uptake May Be at the Core of the Exercise Problems in Chronic Fatigue Syndrome

Taking the Next, er, Step First you document the problem, then you try to figure out what's causing it.  At least three research groups have decided it's time to move past documenting a messed up  energy production system in ME/CFS and to begin figuring what's causing it. Over the next couple Read more [...]

What’s Up in 2014? A Look Ahead for Chronic Fatigue Syndrome

What's up in 2014? Federal funding still sucks, but it's clear that the Research Foundations and non-profits are finding a way.  As the list of studies or trials ending in 2014 indicates, we're going to learn a lot about chronic fatigue syndrome this year. Treatment UK Rituximab Trial Underway - Invest Read more [...]