FM and ME/CFS are often triggered by infections but concluding the role pathogens play in these illnesses has been difficult.
It just got a whole lot easier.
A Harvard researcher recently published a widely lauded paper that describes a quantum leap in researchers ability to assess the influence Read more [...]
We are putting the finishing touches on a creatively disruptive approach for people-powered research. Together we will get to the bottom of ME/CFS. Suzanne Vernon
We were talking subsets at an event about five years ago. Suzanne turned to me and a friend and asked us to tell our stories. As our Read more [...]
There's something about migraines and fibromyalgia and chronic fatigue syndrome (ME/CFS). Migraines aren’t usually talked about as major comorbid disorders with these diseases but recent studies suggest, however, that migraine may be one of the most, if not the most, common comorbid disorder for Read more [...]
"Key transducers of nociception and pain"
Much of the activity in nerve cells is regulated by very small channels that regulate the flows of ions such as calcium, sodium and magnesium in or out of the cells.
Given the central nervous system problems in ME/CFS and FM and the clear role ion channels Read more [...]
The first intimations that chronic fatigue syndrome might be associated with gynecological issues came early in the history of the disorder. In 1988 Dr. Komaroff co-authored a paper finding increased gynecological complications (endometriosis, ovarian cysts, polycystic ovaries, uterine fibroids, Read more [...]
"These results reinforce the proposal of fibromyalgia as a neuropathic pain syndrome. Our results also show that fibromyalgia patients have multiple autonomic dysfunction symptoms." Authors
The destruction of small nerve fibers in the skin of fibromyalgia patients (small fiber neuropathy - SFN) Read more [...]
How a disorder starts can be very informative. A rapid onset illness associated with swollen lymph glands, muscle aches, fatigue and fever so often marks the onset of a short-term infection that rarely do doctors attempt to identify the precipitating pathogen. Other beginnings are more obscure. The Read more [...]
Natural killer cells appear to be the ground zero for the immune dysfunction found in chronic fatigue syndrome. These cells are, as their name implies, killers. They're called "natural" killer cells because in contrast to cytotoxic T-cells which need to be activated to fight infections, NK Read more [...]