Archive for Research

‘Strained’ – Are Neuromuscular Problems Causing Chronic Fatigue Syndrome?

A Different Kind of Neurological Disorder Chronic Fatigue Syndrome (ME/CFS) is sometimes described as a neurological disorder - as if that term described something discrete. When people first spoke of ME/CFS as a neurological disorder they probably meant a central nervous system condition - problems Read more [...]

Could Cancer Research Improve the Treatment of Widespread pain in Fibromyalgia and ME/CFS?

Peripheral Neuropathy in Cancer and Fibromyalgia Billions of dollars are spent annually worldwide on improving the prevention, detection and treatment of cancer. New drugs and treatment modalities are extending survival rates, with recent initial trials even inciting (probably prematurely) speculation Read more [...]

Turning Stress into Pain: A Fibromyalgia Primer by Dr. Martinez-Lavin Pt I – Pain

A Mexico City doctor and researcher, Dr. Manuel Martinez-Lavin, has been studying and treating people with Fibromyalgia for over thirty years. In a 2009 paper he proposed two pathways for Fibromyalgia. One suggested that over-activation of the sympathetic nervous system fibers (sprouting) Read more [...]

Immersed: How I Found a Way (After Decades of Trying) to Help My Allodynia and Nerve Pain

I suspect many you are like me: there is something dramatically wrong with your body and it has been that way for quite a while.  You surf the ups and downs of your symptoms and occasionally wonder, "What does this symptomatic change mean?" If you are like me, you have learned that most medical Read more [...]

Knackered Nerves: Do Low BDNF Levels Spell Nerve Exhaustion in Chronic Fatigue Syndrome? Pt. I

“The decreased production [of BDNF] in those with CFS was unexpected and a novel finding. This finding could reflect a reduced ability to maintain neuronal structure and function in … CFS.” Authors Chronic fatigue syndrome and multiple sclerosis don’t get paired in studies very often, Read more [...]

Are Both Small AND Large Fiber Neuropathy Present in Fibromyalgia?

We report here a surprisingly high prevalence of clinical and electrodiagnostic (EDX) abnormalities implying a demyelinating polyneuropathy, suggestive of chronic inflammatory demyelinating polyneuropathy (CIDP), in FMS. Caro et. al 2008 With three studies finding evidence of small fiber neuropathy Read more [...]

The Kitei-Lipkin Interview: Missing Pathogens, Psychosomatic Directors and Serving the Chronic Fatigue Syndrome Community

Mindy Kitei just posted a long interview with Ian Lipkin, the renowned 'virus-hunter' leading the Chronic Fatigue Initiative's ME/CFS pathogen discovery project. Dr. Lipkin has also begun a crowdfunding effort to raise the funds to do comprehensive microbiome analyses in people with Chronic Fatigue Read more [...]

The Blood (Volume) Will Out: Is Ischemia A Key in Both POTS and Chronic Fatigue Syndrome?

Brain Blood Flows in ME/CFS and POTS We've been looking at postural orthostatic tachycardia syndrome (POTS) lately. It's clear that about fifty percent of POTS patients meet the criteria for ME/CFS and a much smaller percentage of ME/CFS patients probably meet the criteria for POTS. The question Read more [...]