Archive for Brain

Knackered Nerves: Do Low BDNF Levels Spell Nerve Exhaustion in Chronic Fatigue Syndrome? Pt. I

“The decreased production [of BDNF] in those with CFS was unexpected and a novel finding. This finding could reflect a reduced ability to maintain neuronal structure and function in … CFS.” Authors Chronic fatigue syndrome and multiple sclerosis don’t get paired in studies very often, Read more [...]

The Fatigue and Pain Producers: Could Glial Cells Be ‘It’ in Chronic Fatigue Syndrome and Fibromyalgia?

It became evident that glial activation was not merely just correlated with pain, but that it was critically involved in inducing pathological pain. Suddenly glial cells are turning up in spades in Chronic Fatigue Syndrome and Fibromyalgia.  The Japanese neuroinflammation study found widespread Read more [...]

Neuroinflammation: Putting the ‘itis’ back into Myalgic Encephalomyelitis – Back to the Future For Chronic Fatigue Syndrome?

“Our results provide evidence of neuroinflammation in CFS/ME patients, as well as evidence of the possible contribution of neuroinflammation to the pathophysiology of CFS/ME.“ 'Show Me the Inflammation!' It’s perhaps emblematic of a complex and difficult to nail down illness such as ME/CFS Read more [...]

Shape Shifting Pain: How Chronic Pain Turns the Brain More ‘Emotional’

Recently we saw that some people appear to be sitting ducks for chronic pain.  Their brains have apparently reached a state, unbeknownst to them, where all that's needed for a chronic pain state to emerge is a triggering event such as an injury. That triggering even starts a process which changes Read more [...]

Bad Wiring: Were You Set Up for Poor Health? A Source of Chronic Pain Illuminated

The Pain Mystery It's an incredible thing; Americans spend up to 600 billion (billion with a B) dollars to treat pain. Almost 30% percent of people with pain have low back pain and about 25% of them have chronic low back pain. You'd think with that many people in pain we'd be pretty far along Read more [...]

A Neuropsychologist Looks at ME/CFS – Part II of ‘Cognition – What do We Know?’: IQ, Walking and Chewing Gum, A Missing Test, Treatment

In Part II of the A Neuropsychologist Looks at ME/CFS, Dr. Lange looks at neuropsychological testing, IQ, we riff on how cognitive problems can affect how well you move, and more...See Pt. I below. Brain Burn, Brain Drain and Low Blood Flows: A Neurologist on ‘Cognition and Chronic Fatigue Read more [...]

Brain Burn, Brain Drain and Low Blood Flows: A Neurologist on ‘Cognition and Chronic Fatigue Syndrome – What Do We Know’?’

This overview of the CFIDS Association of America’s webinar on cognition in 2012 was produced while I was with Phoenix Rising but was never published. We just published Dr. Lapps take on cognition and possible ways to treat it. Now, that we've got an overview of the treatment possibilities Read more [...]

Sensory Overload: Study Suggests Brains in Fibromyalgia Are Being Pummeled With Too Much Information

New study provides further evidence that problems with sensory gating may contribute to fibromyalgia pain and other symptoms. It’s a Jungle Out There The key to survival in the animal world is to be able to detect threats in the environment and react appropriately.  From the simplest sea Read more [...]