The Pain Brain
Sometimes you've got to ask wonder where is it going to stop with fibromyalgia (FM) and the brain? Reductions in the volume of "gray matter" (the neuronal cell bodies and glial cells as opposed to the long nerve fibers) have been found in the insular, anterior cingulate cortices Read more [...]
A Central Nervous System Hypothesis of Chronic Fatigue Syndrome
“... neurophysiological and neuroimaging studies in combination with subjective or a newly developed objective evaluation method of chronic fatigue have begun to clarify the mechanisms underlying chronic cognitive fatigue ...”
Deciding Read more [...]
“The decreased production [of BDNF] in those with CFS was unexpected and a novel finding. This finding could reflect a reduced ability to maintain neuronal structure and function in … CFS.” Authors
Chronic fatigue syndrome and multiple sclerosis don’t get paired in studies very often, Read more [...]
It became evident that glial activation was not merely just correlated with pain, but that it was critically involved in inducing pathological pain.
Suddenly glial cells are turning up in spades in Chronic Fatigue Syndrome and Fibromyalgia. The Japanese neuroinflammation study found widespread Read more [...]
“Our results provide evidence of neuroinﬂammation in CFS/ME patients, as well as evidence of the possible contribution of neuroinﬂammation to the pathophysiology of CFS/ME.“
'Show Me the Inflammation!'
It’s perhaps emblematic of a complex and difficult to nail down illness such as ME/CFS Read more [...]
Recently we saw that some people appear to be sitting ducks for chronic pain. Their brains have apparently reached a state, unbeknownst to them, where all that's needed for a chronic pain state to emerge is a triggering event such as an injury. That triggering even starts a process which changes Read more [...]
The Pain Mystery
It's an incredible thing; Americans spend up to 600 billion (billion with a B) dollars to treat pain. Almost 30% percent of people with pain have low back pain and about 25% of them have chronic low back pain.
You'd think with that many people in pain we'd be pretty far along Read more [...]
In Part II of the A Neuropsychologist Looks at ME/CFS, Dr. Lange looks at neuropsychological testing, IQ, we riff on how cognitive problems can affect how well you move, and more...See Pt. I below.
Brain Burn, Brain Drain and Low Blood Flows: A Neurologist on ‘Cognition and Chronic Fatigue Read more [...]