Archive for Brain

The Neuroinflammation Man: Jarred Younger on Inflammation, Fibromyalgia and Chronic Fatigue Syndrome

(This blog is taken from three sources. A radio interview with Jarred Younger, information on the University of Alabama at Birmingham website and an interview I did with him. Thanks to Jarred for his time.) Unlike others, Younger was never phased by the lack  of attention given fibromyalgia and chronic Read more [...]

The Pain Brain: Hippocampal Atrophy Found in Fibromyalgia

The Pain Brain Sometimes you've got to ask wonder where is it going to stop with fibromyalgia (FM) and the brain? Reductions in the volume of "gray matter" (the neuronal cell bodies and glial cells as opposed to the long nerve fibers) have been found in the insular, anterior cingulate cortices Read more [...]

Fatigue Explained? Japanese Assert Brain Damage Causes Fatigue in Chronic Fatigue Syndrome

A Central Nervous System Hypothesis of Chronic Fatigue Syndrome “... neurophysiological and neuroimaging studies in combination with subjective or a newly developed objective evaluation method of chronic fatigue have begun to clarify the  mechanisms underlying chronic cognitive fatigue ...” Deciding Read more [...]

Knackered Nerves: Do Low BDNF Levels Spell Nerve Exhaustion in Chronic Fatigue Syndrome? Pt. I

“The decreased production [of BDNF] in those with CFS was unexpected and a novel finding. This finding could reflect a reduced ability to maintain neuronal structure and function in … CFS.” Authors Chronic fatigue syndrome and multiple sclerosis don’t get paired in studies very often, Read more [...]

The Fatigue and Pain Producers: Could Glial Cells Be ‘It’ in Chronic Fatigue Syndrome and Fibromyalgia?

It became evident that glial activation was not merely just correlated with pain, but that it was critically involved in inducing pathological pain. Suddenly glial cells are turning up in spades in Chronic Fatigue Syndrome and Fibromyalgia.  The Japanese neuroinflammation study found widespread Read more [...]

Neuroinflammation: Putting the ‘itis’ back into Myalgic Encephalomyelitis – Back to the Future For Chronic Fatigue Syndrome?

“Our results provide evidence of neuroinflammation in CFS/ME patients, as well as evidence of the possible contribution of neuroinflammation to the pathophysiology of CFS/ME.“ 'Show Me the Inflammation!' It’s perhaps emblematic of a complex and difficult to nail down illness such as ME/CFS Read more [...]

Shape Shifting Pain: How Chronic Pain Turns the Brain More ‘Emotional’

Recently we saw that some people appear to be sitting ducks for chronic pain.  Their brains have apparently reached a state, unbeknownst to them, where all that's needed for a chronic pain state to emerge is a triggering event such as an injury. That triggering even starts a process which changes Read more [...]

Bad Wiring: Were You Set Up for Poor Health? A Source of Chronic Pain Illuminated

The Pain Mystery It's an incredible thing; Americans spend up to 600 billion (billion with a B) dollars to treat pain. Almost 30% percent of people with pain have low back pain and about 25% of them have chronic low back pain. You'd think with that many people in pain we'd be pretty far along Read more [...]