Archive for Brain – Page 2

Sensory Overload: Study Suggests Brains in Fibromyalgia Are Being Pummeled With Too Much Information

New study provides further evidence that problems with sensory gating may contribute to fibromyalgia pain and other symptoms. It’s a Jungle Out There The key to survival in the animal world is to be able to detect threats in the environment and react appropriately.  From the simplest sea Read more [...]

Is Chronic Fatigue Syndrome (ME/CFS) A Form of Migraine?

"This indicates a large unmet need to diagnose and treat migraine in GWI and CFS" Could chronic fatigue syndrome be a form of migraine? That might not be so wacky an idea as it sounds. About ten years ago Puri and Chaudhuri suggested chronic fatigue syndrome was similar to migraine. In the last two Read more [...]

Japanese Sensory Gating Study Reveals Profound Cognitive Deficits Present in Chronic Fatigue Syndrome

SENSORY GATING PART V – VALIDATION? A - Sensory Gating Deficits and Neuroinflammation in ME/CFS – A Testable Hypothesis Part I – Sensory Gating - Set out a hypothesis that, if tested, ME/CFS patients (in particular those patients that would describe themselves as the 'Wired and Tired' Read more [...]

Your Brain Without Energy: Broken Brain Energy Loop Wipes Out Cognitive Functioning in GWS Patients with Chronic Fatigue Syndrome

(Exercise stress tests suggest a process that provides energy to the brain during exercise and intense mental activity may be broken and causing severe cognitive dysfunction in one group of GWS/ME/CFS patients (decreasers).  A second GWS/ME/CFS group (increasers) with an intact brain lactate processing Read more [...]

The Immune in Neuroimmune: Cytokines, Bugs and NK Cells – Part IV of the Neuroinflammatory Series Continues

(We're in the windup phase of Marco's Neuroinflammatory Series as he explores the role the immune system and pathogens  play in producing the neuroinflammatory state that may underlie chronic fatigue syndrome (ME/CFS) For more on Marco's Neuroinflammatory Series on ME/CFS C - IMMUNE FINDINGS, Read more [...]

Unusual Type of Nerve Damage Causes Fatigue and Pain in People with Gulf War Illness and Chronic Fatigue Syndrome

(Dr. Baraniuk finds damage to a critical nerve pathway that connects regions of the brain involved in fatigue and pain production and autonomic nervous system regulation. The damage, which affects the integrity of the nerve axons, is unusual and suggests GWS and perhaps ME/CFS  are not related to Read more [...]

When Definitions Obscure: A Neuroinflammatory View of Chronic Fatigue Syndrome Pt. IV

A – A PERSONAL PERSPECTIVE ON 'ME/CFS'  I want to make a controversial and potentially unpopular proposal: that ME/CFS is not a discrete disease in any objective sense and that attempting to more rigorously define a 'pure' ME/CFS cohort is futile.   In Parts I to III, I set out what I suggest Read more [...]

Scared Stiff? Exploring Anxiety, Autoimmunity and Infection in Stiff Person Syndrome – A Possible Model For Chronic Fatigue Syndrome

  (Marco digs into a controversial subject in this second of two blogs on Stiff Person Syndrome and ME/CFS - "Is the depression/anxiety present in Stiff Person Syndrome and, possibly by reflection, chronic fatigue syndrome (ME/CFS), a consequence of having a difficult disease or is it an inherent Read more [...]
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