Archive for microglia

From A Brain Asleep To Leptin to Inflammation – Watch the Stanford Symposium on ME/CFS on Video

Stanford did it right. They produced video's of the March 2014 Stanford  Symposium  on ME/CFS and now they're giving us access to them - for free. Some of the most exciting findings in years came out in the Symposium. They include Dr. Unger's excellent introduction to epidemiology in Read more [...]

Drug Repurposing I: Antibiotics to Reduce Microglial Activation in ME/CFS and Fibromyalgia?

Minocycline: far beyond an antibiotic. N Garrido-Mesa, A Zarzuelo and J Gálvez. British Journal of Pharmacology (2013) 169 337–352 337 DOI:10.1111/bph.12139. Tetracyclines and Neuromuscular Disorders. Daniele Orsucci1,*, Michelangelo Mancuso, Massimiliano Filosto and Gabriele Siciliano. Current Read more [...]

Microglial Inhibiting Drugs – Providing Hope for Fibromyalgia and Chronic Fatigue Syndrome (ME/CFS)?

The microglia surround and protect the neurons in our brains and spinal cord. As the main immune defenders in the brain, they spew out an array of inflammatory and neurotoxic substances when activated. When we have a cold these substances cause the symptoms associated with ‘sickness behavior’ Read more [...]

Medical Madness: How the Feds Approved Drugs for Fibromyalgia That Don’t Work Well While Barring Access to One That Might

"Pregabalin, duloxetine, milnacipran, and amitriptyline are the current first-line prescribed agents but have had a mostly modest effect. With only a minority of patients expected to experience substantial benefit, most will discontinue therapy because of either a lack of efficacy or tolerability problems." Read more [...]

The Fatigue and Pain Producers: Could Glial Cells Be ‘It’ in Chronic Fatigue Syndrome and Fibromyalgia?

It became evident that glial activation was not merely just correlated with pain, but that it was critically involved in inducing pathological pain. Suddenly glial cells are turning up in spades in Chronic Fatigue Syndrome and Fibromyalgia.  The Japanese neuroinflammation study found widespread Read more [...]
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